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Transforming The Future of Cancer Detection with Biomarker Blood Tests

Transforming the Future of Cancer Detection

Cizzle Bio is driving a new era in cancer diagnostics, empowering patients and physicians with early-detection biomarker blood tests for cancer developed by the world’s leading experts. Our flagship test, the CIZ1B Biomarker Blood Test for Lung Cancer, is a leading-edge breakthrough in minimally invasive, highly accurate early detection for the world’s deadliest cancer.

Cizzle Bio is driving a new era in cancer diagnostics, empowering patients and physicians with early-detection biomarker blood tests for cancer developed by the world’s leading experts. Our flagship test, the CIZ1B Biomarker Blood Test for Lung Cancer, is a leading-edge breakthrough in minimally invasive, highly accurate early detection for the world’s deadliest cancer.

Lung Cancer 
PROBLEM

Detect Early. Save Lives.

Cancer is one of the leading causes of death worldwide, and late detection drastically reduces survival rates. The need for accurate, cost-effective, early-detection tools has never been more urgent.

LUNG CANCER
Illustration of human lungs with bronchial tubes connecting to the airway.
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Nearly 5,000 lives are lost daily, with 75% of cases diagnosed at advanced stages, when treatment options are limited, and survival rates are low. 1

EARLY DETECTION IS KEY
A water droplet with a checkmark inside it.

Identifying cancer at its earliest stages significantly improves survival rates, giving patients hope for a better future.

The Urgency of Early Detection

Lung cancer is known for its silent progression, often remaining undetected until late stages when treatment options are limited. While early detection is vital to improve cancer survival, only a fraction of high-risk individuals receive routine testing.

LUNG CANCER
SCREENING RATES

Fewer than 6% of the 14.2 million Americans recommended for annual screening undergo testing, leaving millions undiagnosed. 3

SOLUTION

A Revolutionary Biomarker Blood Test

A scientist wearing safety glasses, a face mask, and blue gloves working with a pipette in a laboratory. There are test tubes with colorful liquids and laboratory equipment in the background.

Cizzle Bio leverages cutting-edge biomarker technology to provide a minimally invasive, highly accurate blood test for early lung cancer detection.

Illustration of human lungs with bronchial tubes in a light blue color.

CIZ1B

Biomarker Test for Early Detection of Lung Cancer

0%

Sensitivity

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NPV

  • Sensitivity of 95% for Stage I Detection and Negative Predictive Value (NPV) at 96%. 4
  • A minimally invasive, cost-effective tool that minimizes need for repeated CT scans—reducing false positives, unnecessary follow-ups, and radiation exposure.

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Partnering with Industry Leaders

In collaborating with industry leaders like Moffitt Cancer Center and BBI Solutions, our work is driven by trusted partnerships and cutting-edge research. Together, we’re integrating minimally invasive biomarker blood tests into mainstream healthcare.

Logo of Moffitt Cancer Center with text and a circular emblem.
Logo of BBI Solutions with red circles and red text.

Saving Lives, One Test at a Time

At Cizzle Bio, our driving purpose—Detect Early. Save Lives.—inspires every breakthrough we deliver. By giving patients the power of early action and equipping physicians with precision diagnostics, we’re changing the course of cancer care and saving more lives.

FOR PATIENTS
A young female nurse or healthcare worker in scrubs and a stethoscope around her neck showing a tablet to an elderly woman with short gray hair, wearing a striped shirt. They are smiling and engaging in a friendly discussion inside a well-lit room with large windows.

Take proactive steps.

Learn how to get tested.

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CIZ1B Lung Cancer Blood Test 
FOR PHYSICIANS
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Learn more about how to access our CIZ1B Biomarker Blood Test for Lung Cancer.


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CIZ1B Lung Cancer Blood Test

Join us in the fight against cancer.

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References:

  • Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, Bray F. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021 May;71(3):209-249.)

  • Sung, H., Ferlay, J., Siegel, R. L., Laversanne, M., Soerjomataram, I., Jemal, A., & Bray, F. (2021). Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians, 71(3), 209-249

  • American Lung Association. (2024). State of lung cancer: Key findings. Retrieved October 26, 2025, from https://www.lung.org/research/state-of-lung-cancer/key-findings

  • Coverley D, Higgins G, West D, et al. A quantitative immunoassay for the lung-cancer biomarker CIZ1b in patient plasma. Clin Biochem. 2017;50(6):336-343.